Innovative Journal of Medical Sciences

Newer therapeutic approaches for anti-ulcer drugs-a review

2023-11-23T05:38:49+00:00

The frequency and prevalence of this disease and its consequences have exhibited dramatic variation, according to epidemiological data. There has been a continuing search for an appropriate, palliative, and curative agent for the treatment of peptic ulcer disease using natural materials of plant and animal origin because these medications are complicated, expensive, and poisonous. Antioxidants aid in scavenging free radicals and regulating the oxidative stress that contributes to the development of peptic ulcers.

Is there any correlation between perfume allergy and urobilinogen?

2023-11-23T05:43:53+00:00

The correlation between perfume allergy and urobilinogen is discussed in this research. Urobilinogen is the colorless fluid produced by the reduction of bilirubin. This process normally occurs in the small intestine. The normal range of urobilinogen in urinary tract is below 17 umol/L; hence, its increased or decreased levels show that there is some kind of disease in urinary tract. Some of the main causes of abnormal level of urobilinogen in urine are hemolysis, liver disease, rotor syndrome, congestive heart failure, and bile duct obstruction. Perfumes contain certain chemicals and when the particles of these chemicals enter into the body by inhalation then T-lymphocytes of our immune system are disturbed leading to different allergic response in our body. About 60% of males have urobilinogen in their urine and are also allergic to perfumes while 55% of females have urobilinogen and are allergic to perfumes as well.

Analysis of nutritional status among high school-going adolescent students in Gadag town, Karnataka

2023-11-23T05:47:23+00:00

Background: Adolescents are nutritionally vulnerable because of the nutritional demand of the pubertal spurt. At this age, adequate nutrition, nutritional education, and counseling are critical to halting the consequences and their impact on this population segment. Calorie and micronutrient deficiencies are known to cause growth retardation in children and adolescents. It is recognized that a variety of foods must be consumed to meet nutrient requirements. Dietary diversity is a serious issue among poor populations in the developing world. The extent of variation in nutrient intake that occurs in a homogeneous population is useful. Malnutrition is a major component of school health services because it leads to poor cognitive performance and physical growth in children. Adolescents who have an unbalanced diet are more likely to develop chronic diseases, especially if they live an unhealthy lifestyle. The purpose of this study was to determine the nutritional status and factors influencing the nutritional status among Gadag City high school-going adolescents aged 12–19 years. Objectives: (1) To assess the nutritional status of Gadag City’s high school adolescent students. (2) To explore about the factors that influence the nutritional status of high school students. Materials and Methods: A cross-sectional study was conducted on adolescent students aged 12–19 in Gadag city’s government and private schools. Permission was obtained from the block education officer and principal of the respective school. Students provided informed consent after a brief explanation of the study’s purpose. The data was collected using the proportional sampling technique, with a sample size of 150. Students from both schools were distributed a semi-structured questionnaire. The World Health Organization formula was used to calculate the body mass index. The data was entered into the Excel sheet at the same time. The results were given as a frequency and a percentage. Results: It has been discovered that the nutritional status of private school students in the overweight category is 7.6% higher than that of government school students. When compared to private schools, government schools had 6.4% more underweight students. It has also been discovered that the average weight of students attending government schools is 3.1% higher than that of students attending private schools. One of the major findings of this survey was that overweight students were more prevalent in private schools than in government schools, with less physical activity and junk food consumption being major influencing factors. Conclusion: Students in government schools are more likely to be underweight than students in private schools, according to the current study findings. To address the issue, government school students’ nutritional status should be addressed, and health education and health promotion are important intervention methods.

Assessment of labor room facilities in Community Health Centers, Taluk hospitals, and the Gadag district hospital

2023-11-23T05:50:28+00:00

Background: Maternal and infant mortality are sensitive indicators that provide evidence for describing a country’s health-care system and indicating the current socioeconomic situation. Recognizing the need to prioritize safe and respectful childbirth practices, the Government of India launched the LaQshya-Labour Room Quality Improvement Initiative in March 2018, with the goal of reducing maternal and new-born mortality and morbidity and increasing women’s satisfaction with healthcare. All Government-run medical colleges, district hospitals (DH), community health centers (CHC), sub-district hospitals, and referral units must follow LaQshya guidelines. LaQshya intends to follow guidelines in organizing the infrastructure and protocol of labor rooms and maternity operation theaters. The guidelines provide standards for space, layout, equipment, consumables, and human resources. Objectives: The objectives of the study are as follows: (1) To assess the delivery room’s infrastructure, equipment, and human resources in the CHC, Taluk hospital, and DH. (2) To analyze the maternal and new-born health-care facility and assess the availability of services and essential drugs in the labor room. Materials and Methods: A cross-sectional study was conducted to determine the labor room facilities in Gadag District’s CHC, Taluk hospital, and DH. By obtaining permission from the District Health Officer (DHO) and the relevant officer at the Health Force for conducting the study. The CHCs, Taluk Hospitals (TH), and DHs were chosen using the Universal Sampling Technique. Data for the study were collected using an observational check-list during the course of studying the labor room facility such as infrastructure, equipment, manpower, and delivery room services with essential medicine. Results: The findings revealed that with the exception of the DH, the majority of infrastructure and equipment are available and capable of providing labor room services, but no hospitals have human resources in accordance with Laqshya guidelines. Apart from Nargundtaluk and DHs, no other health facility has a blood bank or a storage unit. In terms of services, all TH and DHs can provide labor room services, whereas CHCs cannot. Almost all essential medications are available in hospitals. Conclusion: Most of the health institutes had the required infrastructure, equipments, drugs, and service provision except human resource and blood storage facilities in taluk hospital and CHCs of Gadag district.

Evaluation of the in vitro phytochemical components of the commercialized traditional medication Trasina

2023-11-23T05:55:01+00:00

Background: Plants are the rich sources of secondary metabolites such as alkaloids, phenols, flavonoids, tannins, saponins, glycosides, terpenoids etc. that possess a wide array of biological properties. Herbal formulation is the therapeutic medicine composed of medicinal plants having lots of phytochemical with pharmacological action. Quantitative analysis of these phyto-constituents is essential for the preparatory medicine. Trasina is a preparatory medicine extensively used to reduced stress and helpful to maintain body’s immunity. To create polyherbal compounds, the active ingredients of plants must first be extracted using a suitable solvent, the solution must then be evaporated, and the residue must then be adjusted to a specific standard. The Indian herbs Withania somnifera, Tinospora cordifolia, Eclipta alba, Ocimum sanctum, and Picrorrhiza kurroa, which are excellent under stressful circumstances, are the major ingredients in Trasina®, which is marketed as a multi-herbal capsule. Disease-curing phytochemicals included in natural therapies include flavonoids, glucosinolates, saponins, amino acids, monoterpenes, and others. Targets and goals: The purpose of this investigation was to find out if Trasina® included any phytochemical components. Methods: The material was extracted using ethanol, methanol, and aqueous solutions. Several phytochemical components were screened using a recognized technique. Results: In our study the multi herbal formulation (Trasina®) contained various phytochemicals like saponins, flavonoids, steroids, terpenoids, triterpenoids, alkaloids, sugars, anthraquinone, phenolic compounds, and glycosides. Conclusion: The phytochemical constituents of the material were found to include saponins, flavonoids, steroids, terpenoids, triterpenoids, alkaloids, carbohydrates, anthraquinone, phenolic compounds, and glycosides. The pharmacopoeial limitations were met for analytical research parameters such loss on drying, total ash, acid-soluble ash, and pH. The presence of active components may have therapeutic qualities significant for pharmacological activity, according to preliminary phytochemical screening