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Nursing career is one of the fastest rising sectors all over the world. But Nurses and nursing profession are both deserted in Bangladesh. The study is an attempt to assess the socio-economic condition of the nurses at Sylhet district. A total of 151 nurses of both male and female are interviewed by a structure questionnaire. Descriptive statistics and multiple linear regression model are applied to analyze the data. The result depicts that majority of the nurses are from Sylhet division and the female nurses (95.4%) are comparatively more than that of male nurses. Majority (59.6%) of the nurses are married. The findings also show that more than two-third of the nurses have accomplished nursing diploma course. Most of the nurses (76.8%) are satisfied with their job. Average monthly income of the nurses is 27,843 (in Tk.). Only a few nurses (30.5%) have received training. The multiple linear regression analysis shows that nurse’s satisfaction level and length of service are significant factors associated with their income.